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Management of cutaneous dermatomyositis

Identifieur interne : 001379 ( Main/Exploration ); précédent : 001378; suivant : 001380

Management of cutaneous dermatomyositis

Auteurs : Christina Lam [États-Unis, Canada] ; Ruth Ann Vleugels [États-Unis]

Source :

RBID : ISTEX:F2D22B15210E06F4F86113EECB18B603F49B177B

English descriptors

Abstract

Dermatomyositis (DM) is traditionally classified as an idiopathic inflammatory myopathy distinguished by muscle weakness and characteristic cutaneous findings. Patients presenting with the skin manifestations in the absence of clinical evidence of muscle weakness are categorized as clinically amyopathic DM. The symptoms associated with the cutaneous findings can be particularly debilitating, and a discordant response to therapy exists between muscle and skin disease. Various therapeutic agents and treatment approaches have been described, both for the cutaneous and extracutaneous manifestations; however, a paucity of controlled studies in this disease leads to limitations in interpreting the available data. In this review, emphasis is placed specifically on summarizing the current literature regarding management of cutaneous DM. In addition, an algorithmic approach to treatment of skin disease is presented.

Url:
DOI: 10.1111/j.1529-8019.2012.01491.x


Affiliations:


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Le document en format XML

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<term>Antimalarial</term>
<term>Antipruritic</term>
<term>Arch dermatol</term>
<term>Arthritis rheum</term>
<term>Autoimmune</term>
<term>Azathioprine</term>
<term>Cadm</term>
<term>Calcineurin</term>
<term>Calcinosis</term>
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<term>Case series</term>
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<term>Cnis</term>
<term>Comorbidities</term>
<term>Complete resolution</term>
<term>Corticosteroid</term>
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<term>Cutaneous disease</term>
<term>Cutaneous lesions</term>
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<term>Cyclophosphamide</term>
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<term>Methotrexate</term>
<term>Methylprednisolone</term>
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<term>Photoprotection</term>
<term>Polymyositis</term>
<term>Pruritus</term>
<term>Randomized</term>
<term>Refractory</term>
<term>Refractory cutaneous</term>
<term>Retrospective</term>
<term>Retrospective study</term>
<term>Rheum</term>
<term>Rheumatoid arthritis</term>
<term>Rheumatol</term>
<term>Rheumatology</term>
<term>Rituximab</term>
<term>Side effects</term>
<term>Skin disease</term>
<term>Skin lesions</term>
<term>Sontheimer</term>
<term>Steroid</term>
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<term>Successful treatment</term>
<term>Systemic</term>
<term>Systemic corticosteroids</term>
<term>Tacrolimus</term>
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<term>Universalis</term>
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